Association Between Erythrocyte Indices and COVID-19 Severity

Ruslie, Geraldo Axel, Suwasanti, Niluh, Darmadi, Epriyanto T., Tahalele, Paul L and Novita, Bernadette Dian (2023) Association Between Erythrocyte Indices and COVID-19 Severity. Asian Journal of Engineering, Social and Health, 2 (11). pp. 1346-1354. ISSN p-ISSN: 29804868, e-ISSN: 29804841

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Abstract

Rapid oxygen desaturation has been widely reported in patients with severe and critical Coronavirus Disease 19 (COVID-19). Recent scientific evidence indicates that this virus can interact with erythrocytes and interfere with the function of hemoglobin as an oxygen carrier. This study aims to analyze the association between the erythrocyte indices and the severity of COVID-19 patients. The current study is a cross-sectional analysis of 120 confirmed COVID-19 cases at the PHC Surabaya hospital. This research was conducted from January 2021 to July 2021. The research data was collected from electronic medical records at the Primasatya Husada Citra Hospital (PHC) Surabaya. Patients in this study were classified as mild-moderate, severe-critical. The Spearman rank correlation test was used for statistical analysis. The erythrocyte indices value decreased in patients with severe-critical grades. According to the Spearman rank correlation test, MCV (r = -468, p=0.000), MCH (r = -337, p=0.000), and MCHC (r = -203, p=0.026) all had a significant correlation with a weak correlation strength. This study demonstrates that there is a significant correlation but with a weak correlation strength, indicating that this parameter cannot be used to predict patient prognosis and severity. Further research is needed for better knowledge regarding COVID-19 and erythrocytes.

Item Type: Article
Uncontrolled Keywords: COVID-19, Erythrocyte Indices, Severity.
Subjects: Medicine
Divisions: Journal Publication
Depositing User: F.X. Hadi
Date Deposited: 28 Nov 2025 03:06
Last Modified: 28 Nov 2025 03:06
URI: https://repositori.ukwms.ac.id/id/eprint/44815

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