Wound healing activity and flavonoid contents of purslane (Portulaca grandiflora) of various varieties

Budiawan, Antonius ORCID: https://orcid.org/0000-0003-3730-3913 (2023) Wound healing activity and flavonoid contents of purslane (Portulaca grandiflora) of various varieties. RSC Advances, 13 (15). pp. 9871-9877. ISSN 2046-2069

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Abstract

Purslane has various varieties with different active metabolite contents that need to be explored further to find each variety's activity in wound healing. Different purslane herbs showed different antioxidant activities, suggesting they will have different flavonoid content and wound healing activity. This research aimed to evaluate purslane's total flavonoid content and wound-healing activity. The wounds induced on the rabbit back skin were divided into 6 treatment groups such as negative control, positive control, 10 and 20% purslane herbs extract varieties A, and 10 and 20% purslane herbs extract varieties C. Wounds were treated twice daily for 2 weeks, and measured on day 0, 7, 11, and 14. Total flavonoid content was measured with the AlCl3 colorimetric method. The wounds treated with 10 and 20% purslane herbs extract varieties A (Portulaca grandiflora magenta flower) have 0.32 ± 0.55 and 1.63 ± 1.96 mm wound diameters on day 7 and healed on day 11. The wounds treated with 10 and 20% purslane herbs extract varieties C (Portulaca grandiflora pink flower) showed 2.88 ± 0.51 and 0.84 ± 1.45 mm diameter and healed on day 11. The purslane herb A showed the highest wound healing activity, and purslane varieties A and C total flavonoid contents were 0.55 ± 0.02 and 1.58 ± 0.02% w/w, respectively.

Item Type: Article
Uncontrolled Keywords: Purslane, Portulaca grandiflora, varieties, wound healing, flavonoids
Subjects: Widya Mandala Catholic University on Madiun Campus > Faculty of Vacational > Pharmacy Diploma Study Program
Pharmacy
Divisions: Journal Publication
Depositing User: Antonius Budiawan
Date Deposited: 11 Mar 2025 03:43
Last Modified: 16 Jun 2025 05:59
URI: https://repositori.ukwms.ac.id/id/eprint/42892

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