Widjaja, Jennyfer Sheren, Waworuntu, Gladdy Lysias and Suwasanti, Niluh (2025) Efficacy of antibacterial properties of manihot esculenta crantz peel extract against staphylococcus aureus. Journal of Widya Medika Junior, 7 (2). pp. 125-128. ISSN 26561409
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Abstract
Background: Staphylococcus aureus is a common commensal and pathogenic bacterium found on human skin that can cause various diseases. Soaps and alcohol-based hand sanitizers contain chemicals that can negatively affect skin health, causing irritation and dryness, especially in individuals with risk factors such as eczema. Studies have shown that cassava peel extract contains active metabolite compounds that exhibit antibacterial properties. Objective: This study aims to evaluate the antibacterial efficacy of cassava (Manihot esculenta Crantz) peel extract by assessing its inhibitory and bactericidal effects against Staphylococcus aureus. Methods: This research is an in vitro experimental study with a non-equivalent control group design. The extraction of cassava peel is conducted using a maceration method with 96% ethanol as the solvent. The antibacterial activity test is performed using the broth microdilution method on a 96-well microplate. The test solution employed is cassava peel extract (Manihot esculenta Crantz) at concentrations of 100%, 50%, 25%, 12.5%, 6.25%, and 3.125%. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values are measured using a microplate reader and recorded as optical density (OD) values. Results: The cassava (Manihot esculenta Crantz) peel extract exhibited antibacterial effects against Staphylococcus aureus. The MIC value of cassava (Manihot esculenta Crantz) peel extract was found at a concentration of 6.25%, while the MBC value was found at a concentration of 25%. Conclusion: Cassava peel has been shown to possess antibacterial effects against Staphylococcus aureus.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Cassava peel; Manihot esculenta crantz; Staphylococcus aureus; Antibacterial effect; Minimum inhibitory concentration; Minimum bactericidal concentration |
| Subjects: | Medicine |
| Divisions: | Journal Publication |
| Depositing User: | F.X. Hadi |
| Date Deposited: | 28 Nov 2025 04:41 |
| Last Modified: | 28 Nov 2025 04:41 |
| URI: | https://repositori.ukwms.ac.id/id/eprint/44823 |
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