Ursia, Catharina Clarissa and Putri, Patricia Dian (2023) Through a Microscopic Lens: Skin Microbiome as the Confederate in Atopic Dermatitis. Jurnal Widya Medika, 9 (1). pp. 54-65. ISSN eISSN: 26232723, pISSN: 23380373
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Abstract
Reciprocity between the skin microbiome and the host underlies the occurrence, exacerbation, and severity of atopic dermatitis (AD). However, the role of the skin microbiome in the pathogenesis of AD is yet to be depicted. This review highlights thehost–microbiome interactions which rely on barrier status, microbiome composition, andmicrobe–microbe interactions. A microbiome shift, with an abundance of S. aureus and lower microbial diversity, compromises the skin barrier function. It shows that epidermal barrier defect depletes the protective commensal skin bacteria and demonstrates how dysbiosis of the skin microbiome can lead to AD.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | atopic dermatitis, skin microbiome, dysbiosis. |
| Subjects: | Medicine |
| Divisions: | Journal Publication |
| Depositing User: | F.X. Hadi |
| Date Deposited: | 14 Aug 2025 06:55 |
| Last Modified: | 14 Aug 2025 06:55 |
| URI: | https://repositori.ukwms.ac.id/id/eprint/44398 |
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